The synthesis is given of oxisuran (methylsulphinyl methyl-2-pyridyl ketone) and its metabolites and derivatives, whose structures are 2-Py-CO-CH2-SOxCH3 (X= 0, 1, 2) and 2- Py-CHOR-CH2-SOnCH3 (R= H, Me; n= 0, 1, 2). From the results obtained in the reaction of oxisuran with different reducing agents, a new stereochemical pathway is suggested to explain the stereoselectivity observed in the reduction of β-keto-sulphoxides with DIBAL. ...
