Tandem oxidative amidation of benzyl alcohols with amine hydrochloride salts catalysed by iron nitrate

…, JSY Ngiam, AM Seayad, DT Tuan, CW Johannes…

文献索引：Ghosh, Subhash Chandra; Ngiam, Joyce S.Y.; Seayad, Abdul M.; Tuan, Dang Thanh; Johannes, Charles W.; Chen, Anqi Tetrahedron Letters, 2013 , vol. 54, # 36 p. 4922 - 4925

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被引用次数: 23

摘要

Abstract A tandem process for the oxidative amidation of benzyl alcohols with amine hydrochloride salts has been developed using inexpensive Fe (NO 3) 3 as the catalyst, air and aqueous t-butyl hydroperoxide as oxidants. A wide range of benzamides have been synthesized under mild conditions. This greener amide formation method provides an economical and practical assess to benzamides from readily available and inexpensive ...