Design and modular parallel synthesis of a MCR derived α-helix mimetic protein–protein interaction inhibitor scaffold

W Antuch, S Menon, QZ Chen, Y Lu, S Sakamuri…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 6 p. 1740 - 1743

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被引用次数: 50

摘要

... Bioorganic & Medicinal Chemistry Letters. ... means for the treatment of cancer, we have been interested in the design and discovery of α-helix mimetic PPI inhibitors as potentially novel, apoptosis promoting cancer chemotherapeutic agents, utilizing a chemical genomics type ...