Spectral characterization of novel 3-phenyl-2-substituted quinazoline and fused quinazoline derivatives

…, WSI Abou-Elmagd, SS Abdelwahab…

文献索引：Mahmoud, Mahmoud R.; Abou-Elmagd, Wael S. I.; Abdelwahab, Salwa S.; Soliman, El-Sayed A. Synthetic Communications, 2013 , vol. 43, # 11 p. 1484 - 1490

全文：HTML全文

被引用次数: 5

摘要

3-phenyl-2-thioxo-quinazolin-4(3H)one 1 was utilized for the construction of some novel 2-substituted quinazolin-4(3H)one derivatives through the formation of 2-hydrazinyl quinazolinone, which was used as the key starting material for the synthesis of 2-heteryl quinazolines via the reaction with one carbon donors, β-diketones and β-ketoester. Infrared, 1 H NMR, and mass spectra of the synthesized compounds were discussed. Some of them showed promising anti- ...