Glycoconjugate journal

AuBr3 mediated glycosidations: synthesis of tetrasaccharide motif of the Leishmania donovani lipophosphoglycan

G Sureshkumar, S Hotha

文献索引：Sureshkumar, Gopalsamy; Hotha, Srinivas Glycoconjugate Journal, 2012 , vol. 29, # 4 p. 221 - 230

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被引用次数: 9

摘要

Abstract Tetrasaccharide cap present in lipophosphoglycan of the Leishmania donovani responsible for visceral Leishmaniaisis is synthesized as a fully protected propargyl glycoside. AuBr 3 mediated selective glycosylation of propargyl 1, 2-orthoester in the presence of propargyl glycoside is employed as a key step to obtain propargyl containing oligomers. Further, propargyl tetrasaccharide is connected with a long chain hydrocarbon ...