Synthesis of 3-hydroxyindolin-2-one alkaloids,(±)-donaxaridine and (±)-convolutamydines A and E, through enolization–Claisen rearrangement of 2-allyloxyindolin-3- …
T Kawasaki, M Nagaoka, T Satoh, A Okamoto, R Ukon…
Claisen rearrangement triggered by enolization of 2-allyloxyindolin-3-ones with DBU was performed in order to prepare 3-allyl-3-hydroxyindolin-2-ones. Total synthesis of 3- hydroxyindolin-2-one alkaloids,(±)-donaxaridine, as well as (±)-convolutamydines A and E, was achieved by transformation of the allyl moiety of 3-allyl-3-hydroxyindolin-2-ones.
