Journal of the American Chemical Society

The knoevenagel condensation of aryl alkyl ketones with malononitrile

DT Mowry

文献索引：Mowry Journal of the American Chemical Society, 1945 , vol. 67, p. 1050

被引用次数: 76

摘要

The ammonium acetate-acetic acid catalyzed condensation of acetophenone with malononitrile'in refluxing benzene solution was observed to proceed at a convenient and reproducible rate, the theoretical amount of water being removed in twelve hours. Furthermore, the rate of reaction was not markedly affected by small changes in catalyst concentration. Since a number of related compounds were desired for work in progress in ...