Nouveaux modèles du NADH en série oxazolyl-3 dihydro-1, 4 pyridine: synthèse, réactivité, rôle de la complexation dans la réactivité

P Binay, G Dupas, J Bourguignon…

文献索引：Binay, P.; Dupas, G.; Bourguignon, J.; Queguiner, G. Canadian Journal of Chemistry, 1987 , vol. 65, p. 648 - 655

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被引用次数: 12

摘要

A new class of NADH models is described: they contain the 3-oxazolyl-1, 4-dihydropyridine structure. They have been synthesized by regioselective addition at the 4 position of organometallic derivatives (one of them bearing a chiral group) on 3-(4, 4-dimethyl-2- oxazolyl) pyridine. The 1, 4-dihydropyridine structure is obtained after quaternarization and reduction by sodium dithionite. Quaternarization through Zincke's reaction leads to models ...