Tetrahedron letters

Total synthesis of bioactive frustulosin and frustulosinol

ML Goddard, R Tabacchi

文献索引：Goddard, Mary-Lorene; Tabacchi, Raffaele Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911

全文：HTML全文

被引用次数: 8

摘要

Stereum hirsutum is a pathogenic fungus involved in 'Esca', a trunk wood disease of grapevine. Among the metabolites isolated from the culture medium of this fungus, frustulosin () shows a high phytotoxicity. A new simple and efficient method for the synthesis of frustulosin () and frustulosinol () was developed. Antibacterial activity and phytotoxicity are reported.