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Regioselective metalation of the 4-position of pyridine. New and convenient alkylation and acylation of 3-amino-5-methoxypyridine

Y Tamura, M Fujita, LC Chen, M Inoue…

文献索引:Journal of Organic Chemistry, , vol. 46, # 17 p. 3564 - 3567

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被引用次数: 29

摘要

... (3) The organolithium reagents usually add across the C=N bond of pyridines: Wakefield, B. J., "The Chemistry of Organolithium ... 3566 J. Org. ... The organic layer was washed with saturated aqueous sodium chloride (20 mL), dried over magnesium sulfate, and evaporated in vacuo ...