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Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists

T Sakamoto, M Moriya, Y Haga, T Takahashi…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 6 p. 1564 - 1568

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被引用次数: 14

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 58, 59 and 60 We previously reported discovery of potent phenylpiperazine derivatives Y5 antagonists such as 2 by derivatization of an arylpyrazole lead (1), 50 and 59 which was identified by screening of the MRL chemical collection ...