Structure–activity relationships of 1, 3, 5-triazine-2, 4, 6-triones as human gonadotropin-releasing hormone receptor antagonists

…, Q Xie, S Reijmers, SK Sullivan, Y Sai, C Chen

文献索引：Guo, Zhiqiang; Wu, Dongpei; Zhu, Yun-Fei; Tucci, Fabio C.; Regan, Collin F.; Rowbottom, Martin W.; Struthers, R. Scott; Xie, Qiu; Reijmers, Shelby; Sullivan, Susan K.; Sai, Yang; Chen, Chen Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3685 - 3690

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被引用次数: 14

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... SAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists resulted in potent compounds. The best compound from the series had a binding affinity of 2 nM. ... SAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing ...