Regioselective one pot synthesis of 2??alkyl/aryl??4h??benzo [1, 4] thiazine??3??one via microwave irradiation

S Kamila, B Koh, O Khan, H Zhang…

文献索引：Kamila, Sukanta; Koh, Benjamin; Khan, Omair; Zhang, Hongming; Biehl, Edward R. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1641 - 1646

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被引用次数: 10

摘要

2-Alkyl-4H-benzo [1, 4] thiazine-3-one derivatives have attracted much interest due to their biological functions [1]. For example, they can be used as effective tranquilizers [1b], angiotensin converting enzyme inhibitors [1c], or aldose reductase inhibitors [1d], and some [1, 4] benzothiazines show anticancer activities [2]. These compounds are also attractive targets for library development because their structure contains multiple positions for facile ...