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The Journal of organic chemistry

Structure reassignment and synthesis of jenamidines A1/A2, synthesis of (+)-NP25302, and formal synthesis of SB-311009 analogues

JR Duvall, F Wu, BB Snider

文献索引:Snider, Barry B.; Duvall, Jeremy R. Organic Letters, 2005 , vol. 7, # 20 p. 4519 - 4522

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被引用次数: 51

摘要

The proposed structures of jenamidines A, B, and C (1-3) were revised to jenamidines A1/A2, B1/B2, and C (8-10). Jenamidines A1/A2 (8) were synthesized from activated proline derivative 43 by conversion to 26 in two steps and 50% overall yield. Acylation of 26 with