Efficient synthesis of γ-DDB

J Chang, X Guo, S Cheng, R Guo, R Chen…

文献索引：Chang, Junbiao; Guo, Xiaohe; Cheng, Senxiang; Guo, Ruiyun; Chen, Rongfeng; Zhao, Kang Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2131 - 2136

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被引用次数: 13

摘要

Synthesis of γ-DDB, which is another family member of α-DDB (dimethyl 4, 4′-dimethoxy-5, 6, 5′, 6′-dimethylenedioxybiphenyl-2, 2′-dicarboxylate), is described. The unsymmetric isomer (γ-DDB) was constructed by a linker-directed intramolecular Ullmann coupling reaction, followed by the cleavage of the linker and re-esterification.