Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability

Q Liu, J Wang, SA Kang, CC Thoreen, W Hur…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 13 p. 4036 - 4040

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被引用次数: 10

摘要

... Bioorganic & Medicinal Chemistry Letters. ... c Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; d Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; ...