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(6, 11-Dihydrodibenzo [b, e] thiepin-11-yl) methylamine,(4-methoxy-6, 11-dihydrodibenzo [b, e] thiepin-11-yl)-methylamine and derivatives; Synthesis and …

V Valenta, J Metyš, M Protiva

文献索引:Valenta; Metys; Protiva Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 3 p. 984 - 993

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被引用次数: 2

摘要

Abstract Using the Curtius reaction, the acids VIa and VIv were transformed to the carbamates IVa and IVb which afforded by alkaline hydrolysis the primary amines Ia and Ib. The N-methyl derivatives IIab were obtained by reduction of the carbamates IVa with lithium aluminium hydride. The N, N-dimethyl derivatives IIIab resulted by methylation of the primary amines Iab with formaldehyde and formic acid. The synthesis of the acid VIb was carried ...