Chemistry and physics of lipids

Synthesis of 1-O-alkyl-sn-glycerols and fluorescently labeled analogs from 2, 5-O-methylene-D-mannitol as precursor

B Kleuser, N Schmidt, G Gercken

文献索引：Kleuser, Burkhard; Schmidt, Norbert; Gercken, Guenther Chemistry and Physics of Lipids, 1993 , vol. 66, # 1-2 p. 111 - 122

全文：HTML全文

被引用次数: 3

摘要

Abstract A new approach employing 2, 5-O-methylene-d-mannitol as precursor for the synthesis of naturally occurring and fluorescently labeled alkyl glycerols is described. From 2, 5-O-methylene-d-mannitol, which was prepared according to the method of Ness et al.[1], 2, 2-O-methylene-bis-(3-O-trityl)-sn-glycerol, the central product, was synthesized to an enantiomerically pure molecule in four steps. 1-O-hexadecyl-sn-glycerol was prepared by ...