Convenient Synthesis of Heterocyclic Compounds with Dihydropyrano [3, 4-b] pyridine Scaffold

S Pacquelet, Y Blache, T Kimny…

文献索引：Pacquelet, Sandrine; Blache, Yves; Kimny, Tan; Dubois, Marie-Aleth Lacaille; Desbois, Nicolas Synthetic Communications, 2013 , vol. 43, # 8 p. 1092 - 1100

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摘要

As a part of our research concerning the design of analogs of natural compounds and evaluation of their antitumor activity, we decided to investigate the synthesis of new analogs of camptothecin. [ 8 8. Wall , ME ; Wani , MC ; Cook , CE ; Palmer , KE ; Mc Phail , AT ; Sim , GA Plant antitumor agents, I: Isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata . J. Am. Chem. Soc. 1966 , 88 ( 16 ), ...