Synthesis of spiro heterocyclic nitroxides derived from 4-piperidone

JFW Keana, VS Prabhu, DK Shen

文献索引：Keana, John F. W.; Prabhu, Vaikunth S.; Shen, DeKang Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2365 - 2367

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被引用次数: 7

摘要

agents for magnetic resonance imaging (MRI) application~.~,~ Nitroxides substituted with primary and secondary amino groups5 are particularly versatile owing to the possibility of further modification by way of acylation or alkylation reactions. Amino nitroxides also have potential as indicators of pH using electron spin resonance spectroscopy. 6 For MRI applications, resistance of the nitroxide group toward bioreduction is an important property ...