Phosphonomethylation of anesthesin and radioprotectant activity of the products
VK Khairullin, MA Vasyanina, RZ Musin…
文献索引：Khairullin, V. K.; Vasyanina, M. A.; Musin, R. Z.; Pudovik, A. N.; Batulina, G. G. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 142 - 145 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 191 - 195
We have now~ for the first time, phosphonomethylated anesthesin in order to obtain esters of (p-ethoxycarbonylphenylaminomethyl) phosphonic acid. Three compounds were synthesized and their toxic and radioprotectant properties examined. As is well known, the phosphonomethylation of amines can be effected by reacting them with paraformaldehyde and trialkyl phosphites [2, 3, 6], or by the Kabachnik--Fields reaction with ...
