Tetrahedron

Highly regioselective ring-opening of aziridines with arenesulfinates on water: a facile access to β-amino/vinyl sulfones

R Chawla, AK Singh, LDS Yadav

文献索引：Chawla, Ruchi; Singh, Atul K.; Yadav, Lal Dhar S. Tetrahedron, 2013 , vol. 69, # 6 p. 1720 - 1724

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被引用次数: 11

摘要

We have developed a LiBr catalyzed efficient synthesis of β-amino sulfones from readily available aziridines and sodium sulfinates in good to excellent yields. The synthetic potential of β-amino sulfones has also been demonstrated by their facile conversion to the corresponding vinyl sulfones. The use of water as reaction media, atom-economy and isolation of products by simple filtration in the case of solid β-amino sulfones are certain ...