Abstract Intramolecular CH arylation of imidazole derivatives is carried out in the presence of a palladium catalyst to form fused heteroaromatic compounds. The reaction of imidazole with 2-iodobenzyl bromide with NaH gives the cyclization precursor in an excellent yield. This then undergoes a palladium-catalyzed intramolecular CH arylation at 100 C to form 5H- imidazo [5, 1-a] isoindole in 78% yield.
