Some Derivatives of Alkylene-Bridged 5, 6-Dihydroxyquinoline1a

…, HL Yale, JT Sheehan, J Bernstein

文献索引：Yale; Bernstein Journal of the American Chemical Society, 1948 , vol. 70, p. 254

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被引用次数: 4

摘要

An enhancement of antimalarial activity by modification of the quinoline nucleus in the pa. maquine type occurs when a second RO-group is substituted in the 5-po~ ition. l~~~ This paper deals with the synthesis of related compounds containing the 5, 6-methylenedioxy-, 5, 6-ethylenedioxyand 5, 6-isopropylidenedioxy groups. Compounds of this type have been proposed during the malaria research program, a but apparently no report of their ...