Synthesis and biological activity of 1-aminomethyl-3, 3-diaryl-2-oxoindolines

…, SM Drogovoz, LV Yakovleva, AI Bereznyakova

文献索引：Bolotov, V. V.; Drugovina, V. V.; Drogovoz S. M.; Yakovleva, L. V.; Bereznyakova, A. I. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 1 p. 48 - 51 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 1 p. 58 - 61

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被引用次数: 22

摘要

In this previous study we also established that replacement of the methyl group in this position by halogen atoms (CI, Br) does not not lead to the desired results. In addition, we were unable to carry out aminomethylation when substituents were present in the ortho positions of the aryl groups of I (R= 5-OCHa, Ar= o-C6H, CH3).