tert-Butyl isocyanide revisited as a convertible reagent in the Groebke–Blackburn reaction

…, M Nikulnikov, Y Sandulenko, K Bukhryakov

文献索引：Krasavin, Mikhail; Tsirulnikov, Sergey; Nikulnikov, Mikhail; Sandulenko, Yuri; Bukhryakov, Konstantin Tetrahedron Letters, 2008 , vol. 49, # 51 p. 7318 - 7321

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被引用次数: 27

摘要

tert-Butyl isocyanide can serve as the convertible reagent in Groebke–Blackburn multi- component reactions. The effective removal of the tert-butyl group from the resulting imidazo [1, 2-a] azines and-azoles is achieved on a gram scale in two steps without chromatographic purification.