Synthesis of pyrido [2, 3-h] pyrrolo [1, 2-a] quinoxaline derivatives is described, starting from 5-amino-6-nitroquinoline. The pyrrole ring is obtained by reaction with 2, 5- dimethoxytetrahydrofuran. Cyclization of the pyrazine ring is achieved after reduction of the nitro grouping by intramolecular cyclization of 6-amino-5-(1-pyrrolyl) quinoline derivatives. 1 H nuclear magnetic resonance spectra are studied.