Asymmetric synthesis of 1-aryl-1, 2-ethanediols from arylacetylenes by palladium-catalyzed asymmetric hydrosilylation as a key step
T Shimada, K Mukaide, A Shinohara…
文献索引：Shimada, Toyoshi; Mukaide, Kotaro; Shinohara, Akihiro; Han, Jin Wook; Hayashi, Tamio Journal of the American Chemical Society, 2002 , vol. 124, # 8 p. 1584 - 1585
Double hydrosilylation of arylacetylenes with trichlorosilane catalyzed first by platinum and second by a chiral monophosphine-palladium complex generated the corresponding 1, 2- bis (silyl)-1-arylethanes, the oxidation of which with hydrogen peroxide gave 1-aryl-1, 2-diols of high enantiomeric purity (94-98% ee) in high yields.
