前往化源商城

A new method of synthesizing 7-(2-hydroxy-5-oxo-1-cyclopentenyl) heptanoic acid and related compounds.

H Naora, T Ohnuki, A Nakamura

文献索引:Naora, Hirokazu; Ohnuki, Takashi; Nakamura, Asao Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 7 p. 2401 - 2404

全文:HTML全文

被引用次数: 4

摘要

A useful prostanoid synthon, 7-(2-hydroxy-5-oxo-1-cyclopentenyl) heptanoic acid (3), was prepared from commercially available cyclooctanone in two steps. Nine other related cyclopentanoids which are also valuable synthons for prostaglandins were obtained from 3 in reasonable yields via several steps. The procedure is capable of generating these useful synthons on a laboratory scale.