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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Reactions of the monoxides of 2, 6??disubstituted pyrazines with phosphoryl chloride and acetic anhydride

…, A Imazeki, Y Itoigawa, H Yamada…

文献索引：Ohta, Akihiro; Imazeki, Akiko; Itoigawa, Yohko; Yamada, Hiroko; Suga, Chieko; et al. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 311 - 320

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被引用次数: 10

摘要

Abstract The monoxides of 2, 6-dimethyl-(1), 2, 6-diphenyl-(2), and 2-methyl-6- phenylpyrazines (3) were subjected to the reactions with phosphoryl chloride and acetic anhydride. Some reactions of the chloropyrazines and hydroxypyrazines obtained thus were also investigated.

3-chloro-2-methyl-6-phenylpyrazine 1-oxide结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 1-oxide结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 4-oxide结构式

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~65%

2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 4-oxide结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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3-chloro-6-methyl-2-phenylpyrazine 1-oxide结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 1-oxide结构式

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~30%

2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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Pyrazine, 2,6-diphenyl结构式

Pyrazine, 2,6-d...

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2-chloro-3,5-diphenylpyrazine结构式

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2-chloro-3,5-diphenylpyrazine结构式

2-chloro-3,5-di...

~78%

Pyrazine, 2,6-diphenyl结构式

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Pyrazine, 2,6-diphenyl结构式

Pyrazine, 2,6-d...

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2-chloro-1-oxido-3,5-diphenylpyrazin-1-ium结构式

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2-chloro-3,5-diphenylpyrazine结构式

2-chloro-3,5-di...

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2-chloro-1-oxido-3,5-diphenylpyrazin-1-ium结构式

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2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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3-methyl-5-phenyl-1H-pyrazin-2-one结构式

3-methyl-5-phen...

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2-chloro-5-methyl-3-phenylpyrazine结构式

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3-chloro-2-methyl-6-phenylpyrazine 1-oxide结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 1-oxide结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 4-oxide结构式

2-methyl-6-phen...

~22%

2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 4-oxide结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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3-chloro-6-methyl-2-phenylpyrazine 1-oxide结构式

3-chloro-6-meth...

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-methyl-6-phenylpyrazine 1-oxide结构式

2-methyl-6-phen...

~29%

2-chloro-3-methyl-5-phenylpyrazine结构式

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2-chloro-5-methyl-3-phenylpyrazine结构式

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2-acetoxymethyl-6-methyl-pyrazine结构式

2-acetoxymethyl...

~89%

6-Methyl-2-pyrazinylmethanol结构式

6-Methyl-2-pyra...

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2-氯-3,5-二甲基吡嗪结构式

2-氯-3,5-二甲基吡嗪

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6-Methyl-2-pyrazinylmethanol结构式

6-Methyl-2-pyra...

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3-chloro-2,6-dimethylpyrazine 1-oxide结构式

3-chloro-2,6-di...

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6-Methyl-2-pyrazinylmethanol结构式

6-Methyl-2-pyra...

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2,6-dimethyl-1-oxidopyrazin-1-ium结构式

2,6-dimethyl-1-...

乙酸酐结构式

~11%

6-Methyl-2-pyrazinylmethanol结构式

6-Methyl-2-pyra...

2-acetoxymethyl-6-methyl-pyrazine结构式

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2,6-dimethyl-1-oxidopyrazin-1-ium结构式

2,6-dimethyl-1-...

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6-Methyl-2-pyrazinylmethanol结构式

6-Methyl-2-pyra...

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3-chloro-2,6-dimethylpyrazine 1-oxide结构式

3-chloro-2,6-di...

~93%

2,6-dimethyl-1-oxidopyrazin-1-ium结构式

2,6-dimethyl-1-...

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2-氯-3,5-二甲基吡嗪结构式

2-氯-3,5-二甲基吡嗪

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2,6-dimethyl-1-oxidopyrazin-1-ium结构式

2,6-dimethyl-1-...

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3-acetoxy-2,6-dimethylpyrazine结构式

3-acetoxy-2,6-d...

~94%

3,5-二甲基吡唑2-醇结构式

3,5-二甲基吡唑2-醇

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2-氯-3,5-二甲基吡嗪结构式

2-氯-3,5-二甲基吡嗪

~14%

3,5-二甲基吡唑2-醇结构式

3,5-二甲基吡唑2-醇

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2-chloro-1-oxido-3,5-diphenylpyrazin-1-ium结构式

2-chloro-1-oxid...

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2,6-dichloro-3,5-diphenylpyrazine结构式

2,6-dichloro-3,...

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Pyrazine, 2,6-diphenyl结构式

Pyrazine, 2,6-d...

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2,6-dichloro-3,5-diphenylpyrazine结构式

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2-chloro-3,5-diphenylpyrazine结构式

2-chloro-3,5-di...

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2,6-dichloro-3,5-diphenylpyrazine结构式

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Studies on pyrazines. Part 34. 1 Synthetic approach, stabili...

[Sato, Nobuhiro; Matsumoto, Kaori; Takishima, Masayuki; Mochizuki, Katsura Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 21 p. 3167 - 3172]

Studies on pyrazines. Part 34. 1 Synthetic approach, stabili...

[Sato, Nobuhiro; Matsumoto, Kaori; Takishima, Masayuki; Mochizuki, Katsura Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 21 p. 3167 - 3172]