Enamides are important structural skeletons in various classes of natural products 1 and 2 and they are also valuable synthetic intermediates. 3 and 4 Traditional methods 5, 6, 7, 8 and 9 for enamide synthesis include: acid-catalyzed condensation of amides and aldehydes, 5 Curtius rearrangement of α,β-unsaturated acyl azides, 6 acylation of imines, 7 and Peterson reaction manifold. 8 More recently, transition metal-catalyzed reactions also provide alternative ...
