Tetrahedron letters

Bis (aminophosphine)-nickel complexes as efficient catalysts for alkylation of allylic acetates with stabilized nucleophiles

H Bricout, JF Carpentier, A Mortreux

文献索引：Bricout, Herve; Carpentier, Jean-Francois; Mortreux, Andre Tetrahedron Letters, 1996 , vol. 37, # 34 p. 6105 - 6108

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被引用次数: 39

摘要

The alkylation of a variety of allylic acetates with dimethyl malonate catalysed by nickel- diphosphine complexes is reported. It is shown that in most cases bis (aminophosphine) type ligands lead to much more efficient catalysts than dppb and other usual diphosphines. The use of chiral ligands during the alkylation of 3-acetoxycyclohexene affords dimethyl cyclohex-2-enylmalonate in up to 40% ee.