New synthesis of pyrrolo-1, 4-benzodiazepines by utilizing palladium-catalyzed carbonylation.

森美和子， /石倉稔， 伴義雄, Y BAN

文献索引：Mori; Purvaneckas; Ishikura; Ban Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3840 - 3847

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被引用次数: 11

摘要

A pyrrolo-1, 4-benzodiazepine skeleton which constitutes the common part of a series of antibiotics exhibiting antitumor activity was synthesized by insertion of carbon monoxide into o-bromoprolylaniline derivatives in the presence of a catalytic amount of Pd (OAc) 2 and