Tetrahedron letters

Isomerization and ring-closing metathesis for the synthesis of 6-, 7-and 8-membered benzo-and pyrido-fused N, N-, N, O-and N, S-heterocycles

…, SD Khanye, BAA Aderibigbe, JP Michael, DG Billing

文献索引：Van Otterlo, Willem A.L.; Morgans, Garreth L.; Khanye, Setshaba D.; Aderibigbe, Blessing A.A.; Michael, Joseph P.; Billing, David G. Tetrahedron Letters, 2004 , vol. 45, # 50 p. 9171 - 9175

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被引用次数: 64

摘要

An isomerization–ring-closing metathesis (RCM) strategy afforded N-substituted 4H-1, 4- benzoxazines from the protected N-allyl-2-(allyloxy) anilines. In addition, RCM was used to synthesize the N-substituted, 8-membered benzo-fused heterocycles from the respective diallyl compounds: 1, 2, 5, 6-tetrahydro-1, 6-benzodiazocine, 5, 6-dihydro-2H-1, 6- benzoxazocine, 5, 6, 9, 10-tetrahydropyrido [2, 3-b][1, 4] diazocine and 5, 6-dihydro-2H-1, ...