前往化源商城

Tetrahedron

Novozym 435-catalyzed kinetic resolution of β-allenols. A facile route for the preparation of optically active β-allenols or allenyl acetates

D Xu, Z Lu, Z Li, S Ma

文献索引:Xu, Daiwang; Lu, Zhan; Li, Zuyi; Ma, Shengming Tetrahedron, 2004 , vol. 60, # 51 p. 11879 - 11887

全文:HTML全文

被引用次数: 22

摘要

A variety of optically active β-allenols and β-allenyl acetates were synthesized via the Novozym 435-mediated kinetic resolution of racemic β-allenols. A dramatic solvent effect was observed for the stereoselectivity. The scope of the substrates and the effect of the concentration and temperature on the reaction were also investigated.

 相关合成线路

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%