Cross-coupling reaction of α-chloroketones and organotin enolates catalyzed by zinc halides for synthesis of γ-diketones

M Yasuda, S Tsuji, Y Shigeyoshi…

文献索引：Baba, Akio; Yasuda, Makoto; Yano, Katsunori; Shibata, Ikuya; Matsuda, Haruo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 3205 - 3207

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被引用次数: 49

摘要

The reaction of tin enolates 1 with α-chloro-or bromoketones 2 gave γ-diketones (1, 4- diketones) 3 catalyzed by zinc halides. In contrast to the exclusive formation of 1, 4- diketones 3 under catalytic conditions, uncatalyzed reaction of 1 with 2 gave aldol-type

~76%

~77%

~80%

2108-54-5

1-(4-甲氧基苯基)-1,4-戊二酮

~59%

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