Condensation of 14-bromodaunorubicin with thiols in methanol, in the presence of potassium carbonate, resulted in the formation of 14-thia analogues of the antitumor antibiotic adriamycin. However, similar condensation of N-(trifluoroacetyl)-l4- iododaunorubicin with thiols invariably led to a redox reaction, with the formation of N- (trifluoroacety1) daunorubicin and disulfides. Accordingly, N-(trifluoroacetyl)-14- ...
![N-[6-[[3-(2-dodecylsulfanylacetyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide结构式](https://image.chemsrc.com/caspic/233/83291-70-7.png)
![7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9-[2-[2-[2-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]sulfanylethylsulfanyl]acetyl]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tet结构式](https://image.chemsrc.com/caspic/109/83291-73-0.png)
![7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9-[2-[3-[2-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]sulfanylpropylsulfanyl]acetyl]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-te结构式](https://image.chemsrc.com/caspic/071/83291-74-1.png)
