Microwave??Promoted Selective Mono??N??Alkylation of Anilines with Tertiary Amines by Heterogeneous Catalysis

MC Lubinu, L De Luca, G Giacomelli…

文献索引：Lubinu, M. Caterina; De Luca, Lidia; Giacomelli, Giampaolo; Porcheddu, Andrea Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 82 - 85

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被引用次数: 24

摘要

Alkyl anilines are valuable intermediates broadly used in the chemical industry for the manufacture of pharmaceuticals, dyestuffs, synthetic rubbers, herbicides, insecticides and agrochemicals.[1] Traditional routes for their preparation require N-alkylation of anilines with alkyl halides [2] in the presence of a base, palladium/copper-catalysed amination [3] of aryl halides or the more popular reductive amination of carbonyl compounds.[4] Few of these ...