Homoarcyriaflavin: synthesis of ring-expanded arcyriaflavin analogues

…, T Burgemeister, S Dove, S Kuhr, A Popp

文献索引：Mahboobi, Siavosh; Burgemeister, Thomas; Dove, Stefan; Kuhr, Sabine; Popp, Alfred Journal of Organic Chemistry, 1999 , vol. 64, # 22 p. 8130 - 8137

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被引用次数: 22

摘要

The construction of the ring-expanded carbazole system, forming arcyriaflavin homologues, is efficiently accomplished by the reaction of 2, 2'-bridged bis-indoles with 3, 4-dibromo-2, 5- dihydro-1 H-2, 5-pyrroledione derivatives under Grignard conditions. A ring size of up to nine members in the central ring is achievable. Substitutions either at the indole system or at the imide-N are also possible. The conformation of homoarcyriaflavins as a cross-link ...