An efficient synthesis of quinazoline derivatives with the aid of low??valent titanium reagent

…, J Wang, L Rong, Q Zhuang, X Wang

文献索引：Shi, Daqing; Shi, Chunling; Wang, Juxian; Rong, Liangce; Zhuang, Qiya; Wang, Xiangshan Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 2 p. 173 - 183

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被引用次数: 40

摘要

Abstract Quinazolin-4 (3H)-ones, 1, 2-dihydroquinazolin-4 (3H)-ones, 3, 4- dihydroquinazolines, imidazo [1, 2-c]-quinazolines and 5, 6-dihydroimidazo [1, 2-c] quinazolines were synthesized by the novel reductive reaction of nitro group, NH bond and ortho-ester, aldehydes or ketones promoted by the low-valent titanium reagent (TiCl 4-Zn system). The structures of these compounds were characterized by elemental analysis, IR ...