Reductive free-radical alkylations and cyclisations mediated by 1-alkylcyclohexa-2, 5-diene-1-carboxylic acids

PA Baguley, JC Walton

文献索引：Baguley, Paul A.; Walton, John C. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 13 p. 2073 - 2082

全文：HTML全文

被引用次数: 33

摘要

A range of 1-alkylcyclohexa-2, 5-diene-1-carboxylic acids were prepared by Birch reduction– alkylation of benzoic acid and their efficiency as mediators of alkyl radical chain addition and cyclisation processes was investigated. Reductive alkylations were respectably successful, even with only one or two equivalents of alkene, for secondary, tertiary and benzylic radicals. Reaction of 1-[2-(cyclohex-2-enyloxy) ethyl] cyclohexa-2, 5-diene-1-carboxylic ...