Il Farmaco

Synthesis and antimicrobial activities of N-substituted imides

F Zentz, A Valla, R Le Guillou, R Labia, AG Mathot…

文献索引：Zentz, Frederic; Valla, Alain; Le Guillou, Regis; Labia, Roger; Mathot, Anne-Gabrielle; Sirot, Danielle Farmaco, 2002 , vol. 57, # 5 p. 421 - 426

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被引用次数: 62

摘要

In the field of our research programs concerning novel antimicrobial agents, a series of N- substituted imides was synthesized. These compounds were obtained by cyclization of amido-acids in acetic anhydride/sodium acetate or hexamethyldisilazane/zinc bromide for the hydroxy-aromatic derivatives. The hydroxy-alkyl maleimides were directly prepared by condensation of the corresponding amino-alcohol with maleic anhydride in boiling ...