Tetrahedron

Propylene oxide assisted one-pot, tandem synthesis of substituted-1, 3, 4-oxadiazole-2 (3H)-ones in water

X Yan, S Zhou, Y Wang, Z Ge, T Cheng, R Li

文献索引：Yan, Xu; Zhou, Shuo; Wang, Yuanqiang; Ge, Zemei; Cheng, Tieming; Li, Runtao Tetrahedron, 2012 , vol. 68, # 38 p. 7978 - 7983

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被引用次数: 13

摘要

It has been developed for the synthesis of substituted-1, 3, 4-oxadiazole-2 (3H)-one derivatives via a novel one-pot, tandem procedure assisted by propylene oxide. The 5- substitued-1, 3, 4-oxadiazole-2 (3H)-ones and 3, 5-disubstitued-1, 3, 4-oxadiazole-2 (3H)- ones were, respectively, obtained from three-component reaction of acylhydrazines, carbon disulfide, and propylene oxide, and four-component reaction of acylhydarazines, carbon ...