Anilides bearing a guanidino, thioallophanato, isothioallophanato or amidino group in the ortho position were synthesised (6) for investigations of their anthelmintic effects, and tested against sheep trichostrongylides. The most active anilides are those containing a 5-alkylthio, 5-alkylsulphinyl (alkyl= C3H7, C4H9), 5-phenylthio, 5-phenylsulphinyl or 4- phenylsulphonyloxy group, and a guanidino group substituted at both nitrogen atoms by a ...
