Pharmaceutical research

Synthesis and anti-inflammatory effect of chalcones and related compounds

HK Hsieh, TH Lee, JP Wang, JJ Wang, CN Lin

文献索引：Hsieh, Hsin-Kaw; Lee, Tai-Hua; Wang, Jih-Pyang; Wang, Jeh-Jeng; Lin, Chun-Nan Pharmaceutical Research, 1998 , vol. 15, # 1 p. 39 - 46

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被引用次数: 256

摘要

Abstract Purpose. Mast cell and neutrophil degradations are the important players in inflammatory disorders. Combined with potent inhibition of chemical mediators released from mast cells and neutrophil degranulations, it could be a promising anti-inflammatory agent. 2′, 5′-Dihydroxychalcone has been reported as a potent chemical mediator and cyclooxygenase inhibitor. In an effort to continually develop potent anti-inflammatory ...