Structural features of these chloro-substituted 1, 5-diketones lla-c are shown specifically in their reactions with nucleophilic reagents [5]. Reaction of chlorodiketones lla-c with ammonium acetate in acetic acid led to nucleophilic attack of the reagent on the carbonyl group and cyclization with formation of the 3-chloropyridines IVa-c. Reaction of lla-c with ammonia also gave IVa-c as well as the 2-benzoylpyrroles Va-c produced as a result of ...
