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Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N. epsilon.-branching at lysine during solid-phase peptide synthesis

BW Erickson, RB Merrifield

文献索引:Journal of the American Chemical Society, , vol. 95, p. 3757 - 3763

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被引用次数: 84

摘要

... the apparent first-order rate constant, k, for deprotec- tion of X was determined from the slope of the least- squares line of best fit through data points plotted on a grid of In (Xo/X,) us. ... ( 1969). Journal of the American Chemical Society J 95:11 J May 30, 1973 Page 5. ...