New oxyfunctionalization capabilities for. omega.-hydroxylases. Asymmetric aliphatic sulfoxidation and branched ether demethylation

AG Katopodis, HA Smith, SW May

文献索引：Katopodis, Andreas G.; Smith, Homer A.; May, Sheldon W. Journal of the American Chemical Society, 1988 , vol. 110, # 3 p. 897 - 899

全文：HTML全文

被引用次数: 49

摘要

Abstract: Due to inherent difficulties in the chemical generation of aliphatic synthons, the stereo-and regioselective oxyfunctionalization of simple aliphatic substrates represents an area where chemical applications of biocatalysis would be particularly useful. The hydrocarbon monooxygenase from Pseudomonas oleouorans is a prototypical" w- hydroxylase" known to carry out hydroxylation at the terminal methyl of alkanes as well as ...