Chemo-and Stereoselective Synthesis of Fluorinated Enamides from Ynamides in HF/Pyridine: Second-Generation Approach to Potent Ureas Bioisosteres

B Metayer, G Compain, K Jouvin…

文献索引：Clayden, Jonathan; Lemiegre, Loic; Pickworth, Mark; Jones, Lyn Organic and Biomolecular Chemistry, 2008 , vol. 6, # 16 p. 2908 - 2913

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被引用次数: 10

摘要

... Superacid Group in “Organic Synthesis” Team ... selective enzyme inhibitors,(14, 15) little attention has been paid to their replacement with rigid, stable, and adjustable bioisosteres, which might represent an interesting strategy in medicinal chemistry and chemical biology as ...