Synthesis of 1H-pyridin-2-one derivatives as potent and selective farnesyltransferase inhibitors

L Wang, NH Lin, Q Li, RF Henry, H Zhang…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 18 p. 4603 - 4606

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被引用次数: 14

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Medicinal chemistry efforts led to the discovery of compound 4e with potent cellular activity and good oral bioavailability in dog. ...